Common variations of DNA repair genes are associated with response to platinum-based chemotherapy in NSCLCs.

@article{Li2013CommonVO,
  title={Common variations of DNA repair genes are associated with response to platinum-based chemotherapy in NSCLCs.},
  author={Xian-Dong Li and J Han and Yi-jie Zhang and Hong-bing Li and Xue-Yan Wu},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  year={2013},
  volume={14 1},
  pages={145-8}
}
AIM Individual differences in chemosensitivity and clinical outcome of non-small-cell lung cancer (NSCLC) patients may be induced by host inherited factors. We investigated the impact of XPD Arg156Arg, XPD Asp312Asn, XPD Asp711Asp and XPD Lys751Gln gene polymorphisms on the efficacy of platinum-based chemotherapy in NSCLC patients. METHODS A total of 496 were consecutively selected from the Affiliated Hospital of Nantong University between Jan. 2003 and Nov. 2006, and all patients were… CONTINUE READING
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