Common variants in genes of the postsynaptic FMRP signalling pathway are risk factors for autism spectrum disorders


Autism spectrum disorders (ASD) are heterogeneous disorders with a high heritability and complex genetic architecture. Due to the central role of the fragile X mental retardation gene 1 protein (FMRP) pathway in ASD we investigated common functional variants of ASD risk genes regulating FMRP. We genotyped ten SNPs in two German patient sets (N = 192 and N… (More)
DOI: 10.1007/s00439-013-1416-y


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