Common variants conferring risk of schizophrenia

  title={Common variants conferring risk of schizophrenia},
  author={Hreinn Stef{\'a}nsson and Roel A. Ophoff and Stacy Steinberg and Ole Andreas Andreassen and Sven Cichon and Dan Rujescu and Thomas M. Werge and Olli Pietil{\"a}inen and Ole Mors and Preben Bo Mortensen and Engilbert Sigurdsson and {\'O}mar G{\'u}stafsson and Mette Nyegaard and Annamari Tuulio-Henriksson and Andr{\'e}s Ingason and Thomas Hansen and Jaana Suvisaari and Jouko K. Lonnqvist and Tiina Paunio and Anders Dupont B{\o}rglum and Annette M. Hartmann and Anders Fink-Jensen and Merete Nordentoft and David Michael Hougaard and Bent No̸rgaard-Pedersen and Yvonne B{\"o}ttcher and Jes Olesen and Ren{\'e} Breuer and Hans-J{\"u}rgen M{\"o}ller and Ina Giegling and Henrik Berg Rasmussen and Sally Timm and Manuel Mattheisen and Istv{\'a}n Bitter and J{\'a}nos M R{\'e}thelyi and Brynja Bj{\"o}rk Magn{\'u}sd{\'o}ttir and Thordur Sigmundsson and Pall I. Olason and G{\'i}sli M{\'a}sson and Jeffrey R. Gulcher and Magn{\'u}s Haraldsson and Ragnheidur Fossdal and Thorgeir E. Thorgeirsson and Unnur Thorsteinsd{\'o}ttir and Mirella Ruggeri and Sarah Tosato and Barbara Franke and Eric Strengman and Lambertus A.L.M. Kiemeney and Ingrid Melle and Srdjan Djurovic and L I Abramova and Vasily G. Kaleda and Julio Sanju{\'a}n and Rosa de Frutos and Elvira Bramon and Evangelos Vassos and Gillian Fraser and Ulrich Ettinger and Marco M. Picchioni and N. Walker and Timi Toulopoulou and Anna C. Need and Dongliang Ge and J Yoon and Kevin V. Shianna and Nelson B. Freimer and Rita M. Cantor and Robin M. Murray and Augustine Kong and Vera Golimbet and {\'A}ngel Carracedo and Celso Arango and Javier Costas and Erik G. J{\"o}nsson and Lars Terenius and Ingrid Agartz and Hannes P{\'e}tursson and Markus M. N{\"o}then and Marcella Rietschel and Paul M. Matthews and Pierandrea Muglia and Leena Peltonen and David M. St. Clair and David B. Goldstein and K{\'a}ri Stef{\'a}nsson and David A. Collier},
Schizophrenia is a complex disorder, caused by both genetic and environmental factors and their interactions. Research on pathogenesis has traditionally focused on neurotransmitter systems in the brain, particularly those involving dopamine. Schizophrenia has been considered a separate disease for over a century, but in the absence of clear biological markers, diagnosis has historically been based on signs and symptoms. A fundamental message emerging from genome-wide association studies of copy… 

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