Common type 2 diabetes risk gene variants associate with gestational diabetes.

@article{Lauenborg2009CommonT2,
  title={Common type 2 diabetes risk gene variants associate with gestational diabetes.},
  author={Jeannet Lauenborg and Niels Grarup and Peter Damm and Knut Borch-Johnsen and Torben J\orgensen and Oluf Pedersen and Torben Hansen},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2009},
  volume={94 1},
  pages={145-50}
}
OBJECTIVE We aimed to examine the association between gestational diabetes mellitus (GDM) and 11 recently identified type 2 diabetes susceptibility loci. RESEARCH DESIGN AND METHODS Type 2 diabetes risk variants in TCF7L2, CDKAL1, SLC30A8, HHEX/IDE, CDKN2A/2B, IGF2BP2, FTO, TCF2, PPARG, KCNJ11, and WFS1 loci were genotyped in a cohort of women with a history of GDM (n = 283) and glucose-tolerant women of the population-based Inter99 cohort (n = 2446). RESULTS All the risk alleles in the 11… CONTINUE READING