Common regions of the human frontal lobe recruited by diverse cognitive demands

@article{Duncan2000CommonRO,
  title={Common regions of the human frontal lobe recruited by diverse cognitive demands},
  author={John Duncan and Adrian M. Owen},
  journal={Trends in Neurosciences},
  year={2000},
  volume={23},
  pages={475-483}
}
  • J. Duncan, A. Owen
  • Published 1 October 2000
  • Biology, Psychology
  • Trends in Neurosciences

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References

SHOWING 1-10 OF 102 REFERENCES
The role of the anterior prefrontal cortex in human cognition
TLDR
The results indicate that the fronto-polar prefrontal cortex selectively mediates the human ability to hold in mind goals while exploring and processing secondary goals, a process generally required in planning and reasoning.
Dissociating aspects of verbal working memory within the human frontal lobe: Further evidence for a “process-specific” model of lateral frontal organization
TLDR
The effects of varying the executive requirements of a simple verbal working memory task were explored in 8 subjects, using PET, to establish whether this model generalizes to the verbal domain and provide further evidence that the middorsolateral and midventrolateral frontal cortical areas make distinct functional contributions to memory.
Dissociation in prefrontal cortex of affective and attentional shifts
TLDR
It is demonstrated that disinhibition, or a loss of inhibitory control, can be selective for particular cognitive functions and that different regions of the prefrontal cortex provide inhibitory Control in different aspects of cognitive processing.
The functional roles of prefrontal cortex in episodic memory. II. Retrieval.
TLDR
The results provide evidence for functional specialization of the right prefrontal cortex for discrete cognitive processes during episodic memory retrieval with the hypothesis that this region mediates monitoring processes necessary for optimal recall.
Evidence for a two-stage model of spatial working memory processing within the lateral frontal cortex: a positron emission tomography study.
TLDR
P positron emission tomography with magnetic resonance imaging is used to demonstrate the existence of two functionally distinct subdivisions of the lateral frontal cortex, which may subserve different aspects of spatial working memory.
A Parametric Study of Prefrontal Cortex Involvement in Human Working Memory
TLDR
Functional magnetic resonance imaging is used to probe PFC activity during a sequential letter task in which memory load was varied in an incremental fashion, providing a "dose-response curve" describing the involvement of both PFC and related brain regions in WM function.
The functional roles of prefrontal cortex in episodic memory. I. Encoding.
TLDR
The findings indicate that a key function of left dorsolateral PFC at encoding relates specifically to the use of executive processes necessary for the creation of an organizational structure.
Redefining the functional organization of working memory processes within human lateral prefrontal cortex
TLDR
PET dissociation provides unambiguous evidence that the mid‐dorsolateral and mid‐ventrolateral frontal cortical areas make distinct functional contributions to spatial working memory and corresponds with a fractionation of working memory processes in psychological terms.
Brain regions associated with acquisition and retrieval of verbal episodic memory
TLDR
The results provide clear evidence that episodic memory involves a network of specific prefrontal and posterior structures which can be fractionated into different component processes.
Mechanisms of Cognitive Control: Active Memory, Inhibition, and the Prefrontal Cortex
TLDR
A theory is presented that attempts to resolve some of the apparent conflicts between the predominant views on PFC control functions and proposes that PFC performs both mnemonic and inhibitory functions in the service of control.
...
...