Common pathways to tumor rejection.

  title={Common pathways to tumor rejection.},
  author={Ena Wang and Davide Bedognetti and Sara Tomei and Francesco M. Marincola},
  journal={Annals of the New York Academy of Sciences},
The control of tumor growth by the host's immunosurveillance is centered on the activation of interferon (IFN) pathways. In particular, direct study of tumors by various groups has uncovered an IFN-γ-related signature whose presence is consistently associated with better prognosis, predisposition to respond to immunotherapy, and, in its extreme… CONTINUE READING