Common mutations of familial hypercholesterolemia patients in Taiwan: characteristics and implications of migrations from southeast China.

@article{Chiou2012CommonMO,
  title={Common mutations of familial hypercholesterolemia patients in Taiwan: characteristics and implications of migrations from southeast China.},
  author={K R Chiou and M C Charng},
  journal={Gene},
  year={2012},
  volume={498 1},
  pages={100-6}
}
Familial hypercholesterolemia (FH) is an autosomal dominant disease caused by mutations in low-density lipoprotein receptor (LDLR), apolipoprotein B-100 (APOB), and proprotein convertase subtilisin/kexin type 9 (PCSK9) genes. This study investigated FH patients carrying common mutations in Taiwan and compared them to FH southeastern Asians. Causal FH… CONTINUE READING