Common mullein (Verbascum thapsus L.): recent advances in research

@article{Turker2005CommonM,
  title={Common mullein (Verbascum thapsus L.): recent advances in research},
  author={Arzu Ucar Turker and Ekrem Gurel},
  journal={Phytotherapy Research},
  year={2005},
  volume={19}
}
Common mullein (Verbascum thapsus L.) is a medicinal plant readily found in roadsides, meadows and pasture lands and has been used to treat pulmonary problems, inflammatory diseases, asthma, spasmodic coughs, diarrhoea and migraine headaches. Although it has been used medicinally since ancient times, the popularity of common mullein has been increasing commercially for the past few years. Today, the dried leaves and flowers, swallow capsules, alcohol extracts and the flower oil of this plant… 
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An updated, comprehensive, and critical evaluation of various health‐promoting and disease‐mitigating properties of V. thapsus demonstrates various biological and pharmacological properties, including antiviral, antioxidant, analgesic, sedative, anti‐inflammatory, hypnotic, antibacterial, antifungal, as well as anticancer activities.
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The present review attempts to provide an up-to-date comprehensive overview on phytochemical and pharmacological aspects of Verbacum spp.
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The high anti-inflammatory effects of aucubin and the remarkable antioxidant (antiradical) properties of the extracts give scientific support to the traditional use of V. calvum flowers for the preparation in Kurdistan of remedies to cure skin burns and inflammations.
Cultivation Studies of Verbascum thapsus L, the Great Mullein in Trans-himalayan Ladakh Region
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The active ingredient in Verbascum thapsus includes flavonoids like 3 methylguercitin, hesperedin and verbascoside; polysaccharides; iridoid glycosides including harpagoside and aucubin and saponins and volatile oils.
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According to the pharmaceutical traits and the ingredients’ properties extant in Verbascum spp.
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Orange mullein is a biennial plant belonging to the figwort (Scrophulariaceae) family. The vivid yellow flowers are arranged in spikes located on the top of the stem. It is a drought and…
Extensive Phytochemistry, Comprehensive Traditional Uses, and Critical Pharmacological Profile of the Great Mullein: Verbascum thapsus L
TLDR
The aim of the present review is to summarize ethnopharmacology and past/recent studies on phytochemistry, plant profile, botany and pharmacological profile of V. thapsus and updates related information regarding the potential therapeutic targets and new metabolites isolated from V. Thapsus.
Genotoxic Evaluation of a Methanolic Extract of Verbascum Thapsus using Micronucleus Test in Mouse Bone Marrow
TLDR
The methanolic extract of V. thapsus at doses of 100, 300 and 500 mg / kg, did not produce a significant increase in the frequency of MNPCE in bone marrow and neither altered the relationship PCE / NCE respect to negative control.
Traditional Uses and Biological Activities of Verbascum Species
  • Medicine, Biology
TLDR
The usage of Verbascum species to treat respiratory disorders, hemorrhoids, rheumatic pain, inflammatory skin conditions, wounds, fungal infections and diarrhea and biological activities are reviewed.
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