Common mechanisms in development and disease: BMP signaling in craniofacial development.

@article{Graf2016CommonMI,
  title={Common mechanisms in development and disease: BMP signaling in craniofacial development.},
  author={Daniel Graf and Zeba Malik and Satoru Hayano and Yuji Mishina},
  journal={Cytokine & growth factor reviews},
  year={2016},
  volume={27},
  pages={129-39}
}
BMP signaling is one of the key pathways regulating craniofacial development. It is involved in the early patterning of the head, the development of cranial neural crest cells, and facial patterning. It regulates development of its mineralized structures, such as cranial bones, maxilla, mandible, palate, and teeth. Targeted mutations in the mouse have been instrumental to delineate the functional involvement of this signaling network in different aspects of craniofacial development. Gene… CONTINUE READING
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