Common genetic variants of lipoprotein lipase that relate to lipid transport in patients with premature coronary artery disease.

@article{Zhang1995CommonGV,
  title={Common genetic variants of lipoprotein lipase that relate to lipid transport in patients with premature coronary artery disease.},
  author={Qin Zhang and J. S. Cavanna and B R Winkelman and Brian S.F. Shine and Werner Gross and Winfried Marz and D. J. Galton},
  journal={Clinical genetics},
  year={1995},
  volume={48 6},
  pages={293-8}
}
Two common coding sequence mutations of lipoprotein lipase (serine447-ter, producing a carboxy terminal truncation; and asp9-asn variants) were studied in 329 Caucasian subjects, of whom 243 had angiographic features of premature atheroscelerosis (220 with coronary artery disease; 23 with coronary and peripheral artery disease). As expected, the mean levels of cholesterol, triglycerides, LDL-cholesterol, ApoB and Lp(a) were significantly higher in the arterial disease group than in the controls… CONTINUE READING