Common genetic variants in pre-microRNAs are associated with risk of coal workers' pneumoconiosis

@article{Wang2010CommonGV,
  title={Common genetic variants in pre-microRNAs are associated with risk of coal workers' pneumoconiosis},
  author={Meilin Wang and Yang Ye and Haiyang Qian and Zhifang Song and Xiaomin Jia and Zhengdong Zhang and Jianwei Zhou and Chunhui Ni},
  journal={Journal of Human Genetics},
  year={2010},
  volume={55},
  pages={13-17}
}
microRNAs (miRNAs) are an abundant class of small noncoding RNA molecules thought to be involved in biological functions, including embryonic development, chromosome architecture, cell proliferation and apoptosis. We hypothesized that common variants in the miRNAs are associated with risk of coal workers' pneumoconiosis (CWP). In a case–control study of 496 CWP patients and 513 control subjects frequency matched by exposure years and work types, we genotyped four single-nucleotide polymorphisms… CONTINUE READING

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