Common evolutionary origin of the phage T4 dam and host Escherichia coli dam DNA-adenine methyltransferase genes.

@article{Hattman1985CommonEO,
  title={Common evolutionary origin of the phage T4 dam and host Escherichia coli dam DNA-adenine methyltransferase genes.},
  author={Stanley Hattman and J M Wilkinson and D R Swinton and Samuel L. Schlagman and Paul M Macdonald and G. Mosig},
  journal={Journal of bacteriology},
  year={1985},
  volume={164 2},
  pages={932-7}
}
We compared the known DNA nucleotide and encoded amino acid sequences of the Escherichia coli and bacteriophage T4 dam (DNA-adenine methyltransferase) genes. Despite the absence of any DNA sequence homology, there were four regions (11 to 33 residues long) of amino acid sequence homology containing 45 to 64% identity. These results suggest that the genes for these two enzymes have a common evolutionary origin. 

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