Common critical pathways in embryogenesis and cancer

  title={Common critical pathways in embryogenesis and cancer},
  author={Fergal C Kelleher and David William Fennelly and M{\'a}ir{\'i}n Rafferty},
  journal={Acta Oncologica},
  pages={375 - 388}
Cancer may arise because the developmental programs that create the dramatic alterations in form and structure in embryonic development are potentially corrupted. The cells in our bodies retain memories of these processes and cancer can occur later in life if imperfections occur in the fidelity of these pathways. This article is particularly interested in the phenomenon of epithelial to mesenchymal transition, which occurs in embryogenesis. Also reviewed are the small molecules and pathways… 

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