Common Polymorphisms in the Adiponectin Gene ACDC Are Not Associated With Diabetes in Pima Indians.

@article{Courten2005CommonPI,
  title={Common Polymorphisms in the Adiponectin Gene ACDC Are Not Associated With Diabetes in Pima Indians.},
  author={Barbora Vozarova de Courten and Robert L Hanson and Tohru Funahashi and Robert S. Lindsay and Yuji Matsuzawa and Sachiyo Tanaka and Farook Thameem and Jonathan D. Gruber and Philippe Froguel and Johanna K. Wolford},
  journal={Diabetes},
  year={2005},
  volume={54 1},
  pages={284-9}
}
Adiponectin is an abundant adipose tissue-derived protein with important metabolic effects. Plasma adiponectin levels are decreased in obese individuals, and low adiponectin levels predict insulin resistance and type 2 diabetes. Two variants in the adiponectin gene ACDC have been previously associated with plasma adiponectin levels, obesity, insulin resistance, and type 2 diabetes. To determine the role of genetic variation in ACDC in susceptibility to obesity and type 2 diabetes in Pima… CONTINUE READING