Common Phenotype in Patients With Mitral Valve Prolapse Who Experienced Sudden Cardiac Death.

  title={Common Phenotype in Patients With Mitral Valve Prolapse Who Experienced Sudden Cardiac Death.},
  author={J{\'e}r{\^o}me Hourdain and Marie‐Annick Clavel and Jean-Claude Deharo and Samuel J. Asirvatham and Jean François Avi{\'e}rinos and Gilbert Habib and Fr{\'e}d{\'e}ric Franceschi and Vincent Probst and Nicolas Sadoul and Rapha{\"e}l P. Martins and Christophe Leclercq and Michel Chauvin and Jean Luc Pasqui{\'e} and Philippe Maury and Gabriel Laurent and Michael J. Ackerman and David O. Hodge and Maurice Enriquez-Sarano},
  volume={138 10},
HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou… 

Identification of a high-risk subgroup with malignant mitral valve prolapse who are predisposed to sudden cardiac death. A Review.

Findings of this review propose that sudden cardiac death as a result of malignant arrhythmias arises from automaticity, complex ectopy, and reentry at the level of the fascicles and papillary muscles.

Characteristic Histopathological Findings and Cardiac Arrest Rhythm in Isolated Mitral Valve Prolapse and Sudden Cardiac Death

Individuals with iMVP and sudden death have increased cardiac mass, mitral annulus size, and left ventricular fibrosis compared with a matched cohort, with cardiac arrest caused by ventricular fibrillation.

Malignant Mitral Valve Prolapse: Risk and Prevention of Sudden Cardiac Death

The prevalence and risk factors for a malignant phenotype in mitral valve prolapse characterized by life-threatening ventricular arrhythmias and sudden cardiac arrest and death (SCD) are explored, including mechanistic and pathophysiologic findings and mechanism-based potential therapies.

Presentation and Outcome of Arrhythmic Mitral Valve Prolapse.

Mitral Valve Prolapse and Out-of-Hospital Cardiac Arrest: A Case Report and Literature Review

It is emphasized once again that it is especially important to be able to timely identify patients with mitral regurgitation who are at increased risk of sudden cardiac death so that immediate and effective treatment can be offered.

Left Ventricular Remodeling in Non-syndromic Mitral Valve Prolapse: Volume Overload or Concomitant Cardiomyopathy?

Since technical specifications of imaging modalities impact the evaluation of MR severity and LV remodeling, and therefore might influence clinical decision making in these patients, this review will also discuss assessment of MVP using different Imaging modalities.

Parameters associated with ventricular arrhythmias in mitral valve prolapse with significant regurgitation

In patients with MVP with moderate-to-severe MR, symptomatic VA are relatively frequent and associated with significant MV annular abnormalities, subtle left ventricular function impairment and heterogeneous contraction.

Hybrid Positron Emission Tomography/Magnetic Resonance Imaging in Arrhythmic Mitral Valve Prolapse.

A novel association between degenerative MVP and FDG uptake, a surrogate for myocardial inflammation and/or ischemia is demonstrated, suggesting an ongoing subclinical disease process in patients with chronic severe mitral valve surgery undergoing active surveillance.



Natural History of Asymptomatic Mitral Valve Prolapse in the Community

Clinical and echocardiographic characteristics allow separation of the majority of patients with excellent prognosis from subsets of patients displaying, during follow-up, high morbidity or even excess mortality as direct a consequence of MVP.

Arrhythmic Mitral Valve Prolapse and Sudden Cardiac Death

Comparison-enhanced cardiac magnetic resonance may help to identify in vivo this concealed substrate for risk stratification of ventricular electric instability, an underestimated cause of arrhythmic SCD in young adult women.

Ventricular Tachycardia Originating From the Posterior Papillary Muscle in the Left Ventricle: A Distinct Clinical Syndrome

A distinct syndrome of VT arising from the base of the posterior papillary muscle in the LV by a nonreentrant mechanism is presented and irrigated ablation may be necessary for long-term success.

Prevalence and clinical outcome of mitral-valve prolapse.

The prevalence of mitral-valve prolapse in the general population, as diagnosed with the use of current two-dimensional echocardiographic criteria, was lower than previously reported.