Common NOD2/CARD15 variants are not associated with susceptibility or the clinicopathologic characteristics of sporadic colorectal cancer in Hungarian patients

@article{Lakatos2006CommonNV,
  title={Common NOD2/CARD15 variants are not associated with susceptibility or the clinicopathologic characteristics of sporadic colorectal cancer in Hungarian patients},
  author={Peter L Lakatos and Erika Hitre and Ferenc A. de Szalay and Kerstin Zinober and P{\'e}ter Fuszek and L{\'a}szl{\'o} P{\'e}ter Lakatos and Simon Fischer and J{\'a}nos Osztovits and Orsolya Gemela and G{\'a}bor G{\'a}bor Veres and J{\'a}nos Papp and P Ferenci},
  journal={BMC Cancer},
  year={2006},
  volume={7},
  pages={54 - 54}
}
Epidemiological observations suggest that cancer arises from chronically inflamed tissues. Inflammatory bowel disease (IBD) is a typical example as patients with longstanding IBD are at an increased risk for developing colorectal cancer (CRC) and mutations of the NOD2/CARD15 gene increase the risk for Crohn's disease (CD). Recently, NOD2/CARD15 has been associated with a risk for CRC in some studies, which stemmed from ethnically diverse populations. Our aim was to identify common NOD2/CARD15… CONTINUE READING

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