Common MEFV Mutations in Palestinian Patients with Familial Mediterranean Fever

@article{Ashour2015CommonMM,
  title={Common MEFV Mutations in Palestinian Patients with Familial Mediterranean Fever},
  author={Mohammed J. Ashour and F. Sharif},
  journal={International Journal of Genetics},
  year={2015},
  volume={3},
  pages={50}
}
  • Mohammed J. Ashour, F. Sharif
  • Published 2015
  • Medicine
  • International Journal of Genetics
  • Familial Mediterranean fever (FMF) is an autosomal recessive inflammatory disorder caused by mutations in the MEFV gene that encodes the pyrin protein. The disease is relatively common among people originating from the Mediterranean areas. The aim of this study was to determine the common MEFV gene mutations in 270 Palestinian patients diagnosed with FMF. The patients were screened for four common MEFV gene mutations namely, p.M694V, p.M694I, p.V726A, and p.E148Q using allele-specific… CONTINUE READING

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