Common Cervicovaginal Microbial Supernatants Alter Cervical Epithelial Function: Mechanisms by Which Lactobacillus crispatus Contributes to Cervical Health

@inproceedings{Anton2018CommonCM,
  title={Common Cervicovaginal Microbial Supernatants Alter Cervical Epithelial Function: Mechanisms by Which Lactobacillus crispatus Contributes to Cervical Health},
  author={Lauren Anton and Luz-Jeannette Sierra and Ann M. Devine and Guillermo O Baril{\'a} and Laura M. Heiser and Amy G Brown and Michal A Elovitz},
  booktitle={Front. Microbiol.},
  year={2018}
}
Cervicovaginal (CV) microbiota is associated with vaginal health and disease in non-pregnant women. Recent studies in pregnant women suggest that specific CV microbes are associated with preterm birth (PTB). While the associations between CV microbiota and adverse outcomes have been demonstrated, the mechanisms regulating the associations remain unclear. As the CV space contains an epithelial barrier, we postulate that CV microbiota can alter the epithelial barrier function. We investigated the… CONTINUE READING
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