Commercially manufactured engineered nanomaterials for environmental and health studies: Important insights provided by independent characterization

  title={Commercially manufactured engineered nanomaterials for environmental and health studies: Important insights provided by independent characterization},
  author={Heaweon Park and Vicki H. Grassian},
  journal={Environmental Toxicology and Chemistry},
Environmental and health studies on nanomaterials are appearing in the literature at a rapid pace. These studies will address important issues related to the environmental health and safety (EHS) of nanomaterials. As noted in many recent workshop and agency reports, studies devoted toward the environmental fate and transport, nanomaterial–biological interactions, toxicity, and overall risk assessment of nanomaterials should have nanomaterial characterization as a central component of the study… 

Risks of Nanotechnology to Human Life

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This chapter considers the respiratory system as the main route of exposure to nanoparticles and focuses mainly on metal-based nanomaterials and in vivo models used to evaluate them, and discusses available data for other materials.

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Assessment of the toxicological impact and possible hazard of nano particles to human health and the environment is still in its infancy and quantitative nanoecotoxicological data are required.

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Nanoparticles: Environmental Effects

Silver nanoparticles are the most common nanomaterial currently in commercial production and are predicted to have pervasive release to aquatic environments and Mechanisms of action for AgNPs are discussed and cytotoxic, genotoxic and whole-organism endpoints are reviewed.

Toxicology of nanoparticles.

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This review identifies the challenges that exist within the assessment of NM risk and reflects on what commonly encountered challenges exist and explored how these issues may be resolved.



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This review critiques existing nanomaterial research in freshwater, marine, and soil environments and illustrates the paucity of existing research and demonstrates the need for additional research.

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  • S. Klaine
  • Environmental Science
    Environmental toxicology and chemistry
  • 2009
Nanomaterials present exciting opportunities for the development of new products, enhancement of existing products, and the evolution of innovative medical procedures from drug delivery to imaging.

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It was concluded that although many physical factors can influence toxicity, including nanoparticle composition, it is dissolution, surface area and characteristics, size, size distribution, and shape that largely determine the functional, toxicological and environmental impact of nanomaterials.

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Predicting the potential toxicity of emerging nanoparticles will require hypothesis-driven research that elucidates how physicochemical parameters influence toxic effects on biological systems, and a battery of tests should be developed to uncover particularly hazardous properties.

How meaningful are the results of nanotoxicity studies in the absence of adequate material characterization?

  • D. Warheit
  • Physics
    Toxicological sciences : an official journal of the Society of Toxicology
  • 2008
The development of new products using nanomaterials is exciting because, for a given particle-type, as one moves down the nanoscale, fundamental physical and chemical properties appear to change—often yielding completely new and different physical/chemical properties.

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Despite the fact that there exists several techniques capable of characterizing the nanoparticle sizes, their measurement results from the same sample often deviate from each other at an amount that

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Despite the fact that there exist several techniques capable of characterizing nanoparticle sizes, their measurement results from the same sample often deviate from each other by an amount that is

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