Commercial-scale synthesis of protected 2'-deoxycytidine and cytidine nucleosides.

@article{Divakar2003CommercialscaleSO,
  title={Commercial-scale synthesis of protected 2'-deoxycytidine and cytidine nucleosides.},
  author={K. Divakar and Chitra M Sawant and Y A Mulla and Deepak V Zemse and Sakina M Sitabkhan and Bruce Ross and Yogesh S. Sanghvi},
  journal={Nucleosides, nucleotides & nucleic acids},
  year={2003},
  volume={22 5-8},
  pages={1321-5}
}
Transformation of 2'-deoxyuridine and uridine analogs to protected 2'-deoxycytidine and cytidine analogs has been investigated by two different methods. First, traditional triazolation protocol and second p-nitrophenoxylation method. Our studies conclude that the triazolation method is better and suitable for commercial scale-up.