Commercial preparations of lipoteichoic acid contain endotoxin that contributes to activation of mouse macrophages in vitro.

@article{Gao2001CommercialPO,
  title={Commercial preparations of lipoteichoic acid contain endotoxin that contributes to activation of mouse macrophages in vitro.},
  author={Jian Jun Gao and Qiao Xue and E G Zuvanich and K R Haghi and David C. Morrison},
  journal={Infection and immunity},
  year={2001},
  volume={69 2},
  pages={751-7}
}
Lipoteichoic acids (LTA), cell wall components of gram-positive bacteria, have been reported to induce various inflammatory mediators and to play a key role in gram-positive-microbe-mediated septic shock. In a large number of these studies, investigators used commercially available LTA purified from a variety of gram-positive bacteria, including Staphylococcus aureus, Bacillus subtilis, and Streptococcus sanguis. We report here that, although these commercially available LTA could be readily… CONTINUE READING
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Genetic control of endotoxin responsiveness: the Lps gene revisited, p. 735–750

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