Commercial assays available for insulin-like growth factor I and their use in diagnosing growth hormone deficiency.

@article{Clemmons2001CommercialAA,
  title={Commercial assays available for insulin-like growth factor I and their use in diagnosing growth hormone deficiency.},
  author={David Robert Clemmons},
  journal={Hormone research},
  year={2001},
  volume={55 Suppl 2},
  pages={73-9}
}
Radioimmunoassays of insulin-like growth factor I (IGF-I) are commonly used for screening adults and children for growth hormone (GH) deficiency or excess. There are, however, many problems with such assays. Attempts to resolve these problems have focused on methods of separating IGF-I from its binding proteins, and on reducing inter- and intra-assay variability. In particular, the collection of sufficient high-quality normative data is a major difficulty in many laboratories. Clinical… CONTINUE READING
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