Commentary: Protective Effects of Isorhamnetin on N2a Cell Against Endoplasmic Reticulum Stress-induced Injury Is Mediated by PKC?

@inproceedings{Lu2017CommentaryPE,
  title={Commentary: Protective Effects of Isorhamnetin on N2a Cell Against Endoplasmic Reticulum Stress-induced Injury Is Mediated by PKC?},
  author={Huiqiang Lu},
  year={2017}
}
Neuronal apoptosis is an important pathophysiological factor of Alzheimer’s disease (AD). Inhibition of endoplasmic reticulum stress (ERS)-induced neuronal apoptosis is an effective strategy to deal with AD. In this commentary, we summarize the relationship between AD and ERS injury-induced neuronal apoptosis, and highlight the protective effects and mechanism of isorhamnetin (Iso) against ERS-induced injury in N2a cells. Moreover, this commentary discusses the recent findings in the role of… Expand

References

SHOWING 1-10 OF 25 REFERENCES
Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the expression of its target genes.
  • 72
Mediators of endoplasmic reticulum stress‐induced apoptosis
  • 1,842
  • PDF
ER Stress-Mediated Signaling: Action Potential and Ca2+ as Key Players
  • 85
  • PDF
Mitochondria-cytochrome C-caspase-9 cascade mediates isorhamnetin-induced apoptosis.
  • 83
The flavonol isorhamnetin exhibits cytotoxic effects on human colon cancer cells.
  • 70
ER stress-induced cell death mechanisms.
  • 1,143
  • PDF
...
1
2
3
...