Comment on “Do Neonatal Mouse Hearts Regenerate following Heart Apex Resection”?

  title={Comment on “Do Neonatal Mouse Hearts Regenerate following Heart Apex Resection”?},
  author={Michael I. Kotlikoff and Michael Hesse and Bernd K Fleischmann},
  booktitle={Stem cell reports},
The recent article by Andersen et al. (2014) reports that following resection of the neonatal heart, ‘‘complete regeneration’’ does not occur, and contrasts these results with those of Porrello et al. (2011), who used a similar lesion model. The authors cite our work in support of the fact that complete regeneration does not occur within the neonatal mouse, as we reported that infarction of the neonatal mouse heart is accompanied by inflammatory repair, including CD45 cell influx, fibrosis, and… CONTINUE READING

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  • S. A. Jesty, M. A. Steffey, +8 authors M. I. Kotlikoff
  • Natl. Acad. Sci. USA 109, 13380– 13385.
  • 2012
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