Comment on "MeDIP real-time qPCR of maternal peripheral blood reliably identifies trisomy 21".

@article{Qin2013CommentO,
  title={Comment on "MeDIP real-time qPCR of maternal peripheral blood reliably identifies trisomy 21".},
  author={Han Wen Qin and Michael D Bonifacio and Steven J. McArthur and Andrew McLennan and Tom Boogert and Mark Bowman},
  journal={Prenatal diagnosis},
  year={2013},
  volume={33 4},
  pages={403}
}
We read with interest the recent publication in your journal by Tsaliki et al. titled ‘MeDIP real-time qPCR of maternal peripheral blood reliably identifies trisomy 21’. In a correspondence published in September issue of Nature Medicine, Tong et al. raised technical concerns about this methodology. Experimentally, Tong et al. failed to reproduce the results using 15 normal and 3 trisomy cases. We wish to communicate our preliminary results with colleagues working in this field. We used cell… CONTINUE READING

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