Comment: Dystonia and asterixis in acute thalamic infarct: Proposed mechanism

  title={Comment: Dystonia and asterixis in acute thalamic infarct: Proposed mechanism},
  author={Jamir Pitton Rissardo and Ana Let{\'i}cia Fornari Caprara},
  journal={Annals of Movement Disorders},
  pages={138 - 139}
We hypothesized that the concomitant occurrence of dystonia and asterixis probably occurred due to a lesion in the ventrolateral nucleus of the thalamus [ F i g u re 1 ] . T h e p a t h o p h y s i o l o g y of dystonia can be explained by the interruption in the cortico-striato-pallidothalamo-cortical loop [Figure 1A]. A study by Mitchell et al.[3] described that a lesion in the pathways that lead to the thalamus might interrupt the direct and indirect pathways. However, the indirect pathway… 
2 Citations
Mirtazapine-associated movement disorders: A literature review
The management of MTZ-associated movement disorders (MDs) should be the MTZ withdrawal, except in RLS that other options are possible, and if available, the prescription of a benzodiazepine may reduce recovery time.
Carbamazepine-, Oxcarbazepine-, Eslicarbazepine-Associated Movement Disorder: A Literature Review
It is believed that the study of CBZ contributes not only to the improvement of this drug but also to the knowledge about the drug-induced MD of OXC and ESL.


Dystonia after striatopallidal and thalamic stroke: clinicoradiological correlations and pathophysiological mechanisms
It is suggested that thalamic dystonia might be caused by lesions located in the centromedian or the ventral intermediate nuclei, outside the pallidonigral territory, but leading also to a dysfunction of the cortico-striato-pallido-thalamo-cortical loop of the striatopallidal complex.
Thalamic astasia: Inability to stand after unilateral thalamic lesions
Fifteen patients reported here had astasia related to unilateral thalamic lesions, documented by autopsy and computed tomography in 2 patients and by computed tomographic in 13, which involved primarily the superoposterolateral portion of the thalamus, but spread the rubral region.
Dystonia and asterixis in acute thalamic infarct
A patient is presented with combined dystonia and asterixis following a unilateral thalamic infarct, whose dySTONia persisted on follow up while the asterixi faded away with time.
Unilateral asterixis due to a lesion of the ventrolateral thalamus.
The case of unilateral asterixis in a man with a focal ischaemic lesion of the contralateral ventral thalamus is presented and emphasises the importance of electromyographic analysis in establishing the correct diagnosis of involuntary movements before starting specific treatment.
Asterixis after unilateral stroke: Lesion location of 30 patients
  • J. Kim
  • Medicine, Biology
  • 2001
The author describes 30 consecutive patients with unilateral stroke who had asterixis on presentation, which may be caused by the abnormal control of arm posture maintenance due to functional dysregulation of the brainstem–spinal tracts from the cerebello–brainstem–thalamo–frontal lobe system.
Neural mechanisms of dystonia: Evidence from a 2‐deoxyglucose uptake study in a primate model of dopamine agonist‐induced dystonia
It is suggested that dystonia is characterized by increased activity in the putaminopallidal and pallidosubthalamic pathways, and decreased activity in.
Movement Disorders after Stroke in Adults: A Review
Movement disorders after stroke can be helpful in localizing lesions after stroke, determining the etiology of stroke, may need to be a target for therapy and may importantly influence long term outcome.