Comment: CAPN10 alleles are associated with polycystic ovary syndrome.

  title={Comment: CAPN10 alleles are associated with polycystic ovary syndrome.},
  author={Alejandro Gonz{\'a}lez and Eduardo Abril and Alfredo Roca and Mar{\'i}a Jos{\'e} Arag{\'o}n and Maria Jos{\'e} Figueroa and Pilar Velarde and Jose Luis Royo and Luis Real and Agust{\'i}n Ru{\'i}z},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={87 8},
Polycystic ovary syndrome (PCOS) is characterized by chronic anovulation infertility, hyperandrogenemia, and frequently insulin resistance. This study investigated whether polymorphisms in the CAPN10 gene are related with PCOS etiology. The allelic frequencies and genotypes of CAPN10 polymorphisms UCSNP-44, 43, 19, and 63 were determined in 55 well characterized women with polycystic ovaries and 93 unrelated healthy controls using spectrofluorimetric analyses and real-time PCR. Our data… CONTINUE READING