Commensal-epithelial signaling mediated via formyl peptide receptors.

@article{Wentworth2010CommensalepithelialSM,
  title={Commensal-epithelial signaling mediated via formyl peptide receptors.},
  author={Christy C. Wentworth and Rheinallt M. Jones and Young Man Kwon and Asma Nusrat and Andrew S. Neish},
  journal={The American journal of pathology},
  year={2010},
  volume={177 6},
  pages={2782-90}
}
Commensal bacteria and/or their products engender beneficial effects to the mammalian gut, including stimulating physiological cellular turnover and enhancing wound healing, without activating overt inflammation. In the present study, we observed commensal bacteria-mediated activation of the noninflammatory extracellular signal-regulated kinase[ERK]/mitogen-activated protein kinase and Akt signaling pathways in gut epithelial cells and delineated a mechanism for this bacterially activated… CONTINUE READING
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