CommWalker: correctly evaluating modules in molecular networks in light of annotation bias

Abstract

Motivation Detecting novel functional modules in molecular networks is an important step in biological research. In the absence of gold standard functional modules, functional annotations are often used to verify whether detected modules/communities have biological meaning. However, as we show, the uneven distribution of functional annotations means that… (More)
DOI: 10.1093/bioinformatics/btx706

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