Coming to grips with integrin binding to ligands. - Semantic Scholar

Abstract

Integrins are alphabeta heterodimeric cell-surface receptors that are vital to the survival and function of nucleated cells. They recognize aspartic-acid- or a glutamic-acid-based sequence motifs in structurally diverse ligands. Integrin recognition of most ligands is divalent cation dependent and conformationally sensitive. In addition to this common… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Cited By

Sort by:

Increased integrin alpha5beta1 heterodimer formation and reduced c-Jun expression are involved in integrin beta1 overexpression-mediated cell growth arrest.

Zhengyu Fang, Wantong Yao, +7 authors Xiliang Zha
Journal of cellular biochemistry
2010

Action of Thyroid Hormones, T3 and T2, on Hepatic Fatty Acids: Differences in Metabolic Effects and Molecular Mechanisms

Fabrizio Damiano, Alessio Rochira, Antonio Gnoni, Luisa Siculella
International journal of molecular sciences
2017

Integrins as Therapeutic Targets: Successes and Cancers

Sabine Raab-Westphal, John F. Marshall, Simon L. Goodman
Cancers
2017

Tension in Cancer

Stefanie Löffek, Claus-Werner Franzke, Iris Helfrich
International journal of molecular sciences
2016

Correlation, necessity, and sufficiency: Common errors in the scientific reasoning of undergraduate students for interpreting experiments.

Aaron B Coleman, Diane P Lam, Lara N Soowal
Biochemistry and molecular biology education : a…
2015

Cu2+-RGDFRGDS: exploring the mechanism and high efficacy of the nanoparticle in antithrombotic therapy

Jianhui Wu, Yuji Wang, +7 authors Shiqi Peng
International journal of nanomedicine
2015

Leukocyte integrins: role in leukocyte recruitment and as therapeutic targets in inflammatory disease.

Ioannis Mitroulis, Vasileia I Alexaki, Ioannis Kourtzelis, Athanassios Ziogas, George Hajishengallis, Triantafyllos Chavakis
Pharmacology & therapeutics
2015

1 A unified mechanism for aminopeptidase N - based tumor cell motility and tumor

Chang Liu, Yang Yang, Lang Chen, Yi-Lun Lin, Fang Li
2014

A fluorophore-tagged RGD peptide to control endothelial cell adhesion to micropatterned surfaces.

Corinne A Hoesli, Alain Garnier, Pierre-Marc Juneau, Pascale Chevallier, Carl Duchesne, Gaétan Laroche
Biomaterials
2014

A unified mechanism for aminopeptidase N-based tumor cell motility and tumor-homing therapy.

Chang Liu, Yang Yang, Lang Chen, Yi-Lun Lin, Fang Li
The Journal of biological chemistry
2014

‹
1
2
3
4
5
›

References

Sorry, we couldn't extract any references for this paper.

Slides referencing similar topics

Phenotype change: fibroblast α2β1 integrin binds to collagen ligand
GFOGER hexapeptide • Jul 16, 2017
Fascin 55KDa Integrin α2 150KDa
pFAK 125KDa • May 30, 2017
Matrix rigidity regulates integrin adhesion
Nov 01, 2017
Show More