Coming of age: ten years of next-generation sequencing technologies

  title={Coming of age: ten years of next-generation sequencing technologies},
  author={Sara Goodwin and John D. McPherson and W. Richard McCombie},
  journal={Nature Reviews Genetics},
Since the completion of the human genome project in 2003, extraordinary progress has been made in genome sequencing technologies, which has led to a decreased cost per megabase and an increase in the number and diversity of sequenced genomes. An astonishing complexity of genome architecture has been revealed, bringing these sequencing technologies to even greater advancements. Some approaches maximize the number of bases sequenced in the least amount of time, generating a wealth of data that… 

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