Comet assay on children's leukocytes 8 years after the Chernobyl disaster.

@article{Frenzilli1998CometAO,
  title={Comet assay on children's leukocytes 8 years after the Chernobyl disaster.},
  author={Giada Frenzilli and Adriana Lori and G V Panasiuk and Marco Ferdeghini and Roberto Barale},
  journal={Mutation research},
  year={1998},
  volume={415 1-2},
  pages={151-8}
}
DNA damage, mainly single strand breaks, was evaluated by single cell gel electrophoresis, in leukocytes of 36 healthy and 14 thyroid cancer-affected children prior to radio-therapy. The children come from the Gomel region, one of the areas most heavily radio-contaminated by the Chernobyl fallout. In addition, leukocytes were treated with a challenge dose of bleomycin (BLM, 1.5 micrograms/ml), to assess the presence of an adaptive response (AR) potentially resulting from chronic exposure to… CONTINUE READING

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