Combining the use of solid‐supported transition metal catalysis with microwave irradiation in solution‐phase parallel library synthesis

Abstract

Microwave heating methods have been combined with the use of solid‐supported catalysts to produce small solution‐phase libraries of medicinally‐relevant compounds. Palladium supported on charcoal (Pd/C) has been used to produce libraries of pyrazole compounds for screening in COX II studies via Suzuki cross coupling reactions, while the same catalyst has… (More)
DOI: 10.1023/B:MODI.0000006826.91512.83

9 Figures and Tables

Topics

  • Presentations referencing similar topics