Combining prediction of secondary structure and solvent accessibility in proteins

@article{Adamczak2005CombiningPO,
  title={Combining prediction of secondary structure and solvent accessibility in proteins},
  author={Rafal Adamczak and Aleksey A. Porollo and Jaroslaw Meller},
  journal={Proteins: Structure},
  year={2005},
  volume={59}
}
Owing to the use of evolutionary information and advanced machine learning protocols, secondary structures of amino acid residues in proteins can be predicted from the primary sequence with more than 75% per‐residue accuracy for the 3‐state (i.e., helix, β‐strand, and coil) classification problem. In this work we investigate whether further progress may be achieved by incorporating the relative solvent accessibility (RSA) of an amino acid residue as a fingerprint of the overall topology of the… Expand
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