Combining fMRI and SNP data to investigate connections between brain function and genetics using parallel ICA.

@article{Liu2009CombiningFA,
  title={Combining fMRI and SNP data to investigate connections between brain function and genetics using parallel ICA.},
  author={Jingyu Liu and Godfrey D. Pearlson and Andreas Windemuth and Gualberto Rua{\~n}o and Nora I. Perrone-Bizzozero and Vince D. Calhoun},
  journal={Human brain mapping},
  year={2009},
  volume={30 1},
  pages={241-55}
}
There is current interest in understanding genetic influences on both healthy and disordered brain function. We assessed brain function with functional magnetic resonance imaging (fMRI) data collected during an auditory oddball task--detecting an infrequent sound within a series of frequent sounds. Then, task-related imaging findings were utilized as potential intermediate phenotypes (endophenotypes) to investigate genomic factors derived from a single nucleotide polymorphism (SNP) array. Our… CONTINUE READING
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