Combining drinking water treatment and hand washing for diarrhoea prevention, a cluster randomised controlled trial

@article{Luby2006CombiningDW,
  title={Combining drinking water treatment and hand washing for diarrhoea prevention, a cluster randomised controlled trial},
  author={Stephen P. Luby and Mubina Agboatwalla and John A. Painter and Arshad Altaf and W. L. Billhimer and Bruce H. Keswick and Robert M Hoekstra},
  journal={Tropical Medicine \& International Health},
  year={2006},
  volume={11}
}
Objectives  To evaluate the effectiveness of point of use water treatment with flocculent‐disinfectant on reducing diarrhoea and the additional benefit of promoting hand washing with soap. 
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References

SHOWING 1-10 OF 21 REFERENCES
Reducing diarrhoea in Guatemalan children: randomized controlled trial of flocculant-disinfectant for drinking-water.
TLDR
In settings where families rarely treat drinking-water, a novel flocculant-disinfectant was introduced that reduced the longitudinal prevalence of diarrhoea, especially among children aged < 1 year, among whom diarrhoeas has been strongly associated with mortality.
Household based treatment of drinking water with flocculant-disinfectant for preventing diarrhoea in areas with turbid source water in rural western Kenya: cluster randomised controlled trial
TLDR
In areas of turbid water, flocculant-disinfectant was associated with a significant reduction in diarrhoea among children < 2 years, and this health benefit, combined with asignificant reduction in turbidity, suggests that the floc Vulgarium is well suited to areas with highly contaminated and turbidWater.
Effect of washing hands with soap on diarrhoea risk in the community: a systematic review.
Effect of intensive handwashing promotion on childhood diarrhea in high-risk communities in Pakistan: a randomized controlled trial.
TLDR
In a setting in which diarrhea is a leading cause of child death, improvement in handwashing in the household reduced the incidence of diarrhea among children at high risk of death from diarrhea.
Delayed effectiveness of home-based interventions in reducing childhood diarrhea, Karachi, Pakistan.
TLDR
Home drinking water disinfection and handwashing with soap in Karachi squatter settlements were ultimately effective in preventing diarrhea, but only households of slightly higher socioeconomic status changed their behavior quickly enough to benefit during the first summer.
A randomized controlled trial of household-based flocculant-disinfectant drinking water treatment for diarrhea prevention in rural Guatemala.
TLDR
In a setting where diarrhea was a leading cause of death, intermittent use of home water treatment with flocculant-disinfectant decreased the incidence of diarrhea.
Not just a drop in the bucket: expanding access to point-of-use water treatment systems.
TLDR
Self-sustaining, decentralized approaches to making drinking water safe, including point-of-use chemical and solar disinfection, safe water storage, and behavioral change, have been widely field-tested and merit far greater priority for rapid implementation.
Association of indicators of hygiene behavior with persistent diarrhea of young children
TLDR
It is suggested that behaviors which promote increased exposure of young children to enteric pathogens increase risk of persistent diarrhea.
Is prevalence of diarrhea a better predictor of subsequent mortality and weight gain than diarrhea incidence?
TLDR
Examination of data from Ghana suggests that longitudinal prevalence merits greater attention as a measure of outcome in diarrhea studies, and is more strongly predictive of long-term health outcome than incidence.
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