Combining Two Methods of Sequence Definition in a Convergent Approach: Scalable Synthesis of Highly Defined and Multifunctionalized Macromolecules.

@article{Solleder2017CombiningTM,
  title={Combining Two Methods of Sequence Definition in a Convergent Approach: Scalable Synthesis of Highly Defined and Multifunctionalized Macromolecules.},
  author={Susanne C. Solleder and Steven A. Martens and Pieter Espeel and Filip E Du Prez and Michael A R Meier},
  journal={Chemistry},
  year={2017},
  volume={23 56},
  pages={
          13906-13909
        }
}
The straightforward convergent synthesis of sequence-defined and multifunctionalized macromolecules is described herein. The first combination of two efficient approaches for the synthesis of sequence-defined macromolecules is reported: thiolactone chemistry and the Passerini three-component reaction (P-3CR). The thiolactone moiety was used as protecting group for the thiol, allowing the synthesis of a library of sequence-defined α,ω-functionalized building blocks. These building blocks were… CONTINUE READING
5
Twitter Mentions

Topics from this paper.

Citations

Publications citing this paper.