Combining PARAFAC analysis of HPLC-PDA profiles and structural characterization using HPLC-PDA-SPE-NMR-MS experiments: commercial preparations of St. John's Wort.

@article{Schmidt2008CombiningPA,
  title={Combining PARAFAC analysis of HPLC-PDA profiles and structural characterization using HPLC-PDA-SPE-NMR-MS experiments: commercial preparations of St. John's Wort.},
  author={Bonnie Langford Schmidt and Jerzy W. Jaroszewski and Rasmus Bro and Matthias Witt and Dan Staerk},
  journal={Analytical chemistry},
  year={2008},
  volume={80 6},
  pages={1978-87}
}
Herbal preparations represent very complex mixtures, potentially containing multiple pharmacologically active entities. Methods for global characterization of the composition of such mixtures are therefore of pertinent interest. In this work, chemometric analysis of high-performance liquid chromatography with photodiode-array detection (HPLC-PDA) data from… CONTINUE READING