Combining Neuroprotection With Endovascular Treatment of Acute Stroke: Is There Hope?

@article{Tymianski2017CombiningNW,
  title={Combining Neuroprotection With Endovascular Treatment of Acute Stroke: Is There Hope?},
  author={M Tymianski},
  journal={Stroke},
  year={2017},
  volume={48 6},
  pages={
          1700-1705
        }
}
The goal of any clinical trial is to operationalize a paradigm in which the study enrolls the greatest proportion of responders in a setting that maximizes that study intervention’s treatment effect. Such a trial would have the most power to detect the therapeutic benefit it seeks to evaluate. Importantly, the trial should be grounded in—and consistent with—the preclinical science of the test intervention. Based on this, an acute ischemic stroke (AIS) trial must overcome the following 4… CONTINUE READING
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