Combining NMR and EPR to Determine Structures of Large RNAs and Protein-RNA Complexes in Solution.

@article{Duss2015CombiningNA,
  title={Combining NMR and EPR to Determine Structures of Large RNAs and Protein-RNA Complexes in Solution.},
  author={Olivier Duss and Maxim Yulikov and Fr{\'e}d{\'e}ric H.T. Allain and Gunnar Jeschke},
  journal={Methods in enzymology},
  year={2015},
  volume={558},
  pages={279-331}
}
Although functional significance of large noncoding RNAs and their complexes with proteins is well recognized, structural information for this class of systems is very scarce. Their inherent flexibility causes problems in crystallographic approaches, while their typical size is beyond the limits of state-of-the-art purely NMR-based approaches. Here, we review an approach that combines high-resolution NMR restraints with lower resolution long-range constraints based on site-directed spin… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 124 references

Molecular basis for the wide range of affinity found in Csr/Rsm protein-RNA recognition

  • O. Duss, E. Michel, N. Diarra dit Konte, M. Schubert, F.H.T. Allain
  • Nucleic Acids Research,
  • 2014
Highly Influential
20 Excerpts

DeerAnalysis2006—A comprehensive software package for analyzing pulsed ELDOR data

  • G. Jeschke, V. Chechik, P. Ionita, A. Godt, H. Zimmermann, J Banham
  • Applied Magnetic Resonance,
  • 2006
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…