Combined vaccine regimen based on parenteral priming with a DNA vaccine and administration of an oral booster consisting of a recombinant Salmonella enterica serovar Typhimurium vaccine strain for immunization against infection with human-derived enterotoxigenic Escherichia coli strains.

@article{Lasaro2004CombinedVR,
  title={Combined vaccine regimen based on parenteral priming with a DNA vaccine and administration of an oral booster consisting of a recombinant Salmonella enterica serovar Typhimurium vaccine strain for immunization against infection with human-derived enterotoxigenic Escherichia coli strains.},
  author={Marcio O. Lasaro and Wilson Barros Luiz and Maria Elisabete Sbrogio-Almeida and Luc{\'i}lia Sanae Nishimura and Beatriz Ernestina Cab{\'i}lio Guth and Lu{\'i}s C S Ferreira},
  journal={Infection and immunity},
  year={2004},
  volume={72 11},
  pages={
          6480-91
        }
}
Repeated evidence has demonstrated that combined primer-booster immunization regimens can improve both secreted and humoral immune responses to antigens derived from viral, bacterial, and parasitic pathogens. For the present work, we evaluated the synergic serum immunoglobulin G (IgG) and fecal IgA antibody responses elicited in BALB/c mice who were intramuscularly primed with a DNA vaccine, pRECFA, followed by oral boosting with an attenuated Salmonella enterica serovar Typhimurium vaccine… CONTINUE READING

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Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA / MVA vaccine

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