Combined use of hypothermia and buffering in the treatment of critical respiratory failure.

@article{Wetterberg1992CombinedUO,
  title={Combined use of hypothermia and buffering in the treatment of critical respiratory failure.},
  author={Torbj{\"o}rn Wetterberg and Stig Steen},
  journal={Acta anaesthesiologica Scandinavica},
  year={1992},
  volume={36 5},
  pages={
          490-2
        }
}
A 20-year-old male, recovering from post-traumatic ARDS, subsequently developed pneumonia with extreme hypercapnia (PaCO2 max 19.4 kPa) and hypoxemia (PaO2 min 5.1 kPa), in spite of maximal mechanical ventilation. Hypothermia was induced by surface cooling, reducing the body temperature from 40 degrees C to a mean of 33.3 degrees C. Buffer infusion (1375 mmol) during the first 2 days increased base excess from 3 to 22 mmol/l and pH from 7.16 to a median value of 7.30. Active cooling was… CONTINUE READING
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