Combined use of exhaled hydrogen peroxide and nitric oxide in monitoring asthma.

@article{Horvth1998CombinedUO,
  title={Combined use of exhaled hydrogen peroxide and nitric oxide in monitoring asthma.},
  author={Ildik{\'o} Horv{\'a}th and Louise E Donnelly and Alex Kiss and Sergei A. Kharitonov and S Lim and Kian Fan Chung and Peter J. Barnes},
  journal={American journal of respiratory and critical care medicine},
  year={1998},
  volume={158 4},
  pages={
          1042-6
        }
}
Oxidative stress contributes to airway inflammation and exhaled hydrogen peroxide (H2O2) and nitric oxide (NO) are elevated in asthmatic patients. We determined the concentrations of expired H2O2 and NO in 116 asthmatic (72 stable steroid-naive, 30 stable steroid-treated, and 14 severe steroid-treated unstable patients) and in 35 healthy subjects, and studied the relation between exhaled H2O2, NO, FEV1, airway responsiveness, and eosinophils in induced sputum. Both exhaled H2O2 and NO levels… CONTINUE READING

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