Combined treatment with cyclophosphamide and prednisolone can induce remission of nephrotic syndrome in a patient with renal amyloidosis, associated with rheumatoid arthritis.

@article{Maezawa1994CombinedTW,
  title={Combined treatment with cyclophosphamide and prednisolone can induce remission of nephrotic syndrome in a patient with renal amyloidosis, associated with rheumatoid arthritis.},
  author={Akira Maezawa and Keiju Hiromura and Hideki Mitsuhashi and Yukiko Tsukada and Hiroaki Kanai and Shozo Yano and Tomohiko Naruse},
  journal={Clinical nephrology},
  year={1994},
  volume={42 1},
  pages={30-2}
}
A 67-year-old woman, who had been diagnosed with classical rheumatoid arthritis (RA), was admitted to our hospital because of massive proteinuria. Biopsy of the kidney revealed deposition of amyloid fibrils in the subepithelial and subendothelial spaces of the glomerular capillary walls. Though the treatment with prednisolone and dipyridamole against nephrotic syndrome and amyloidosis due to RA was not effective, cyclophosphamide, which was added after tapering of prednisolone, was able to… CONTINUE READING