Combined treatment with TNF-alpha/gefitinib alleviates the resistance to gefitinib in PC-9 cells.

@article{Ji2009CombinedTW,
  title={Combined treatment with TNF-alpha/gefitinib alleviates the resistance to gefitinib in PC-9 cells.},
  author={Yasheng Ji and Sheng-lin Ma and Yi Zhang and Jing Tang and Yan-Ming Wu and Yan-jun Lu},
  journal={Anti-cancer drugs},
  year={2009},
  volume={20 9},
  pages={832-7}
}
Gefitinib has been approved for the treatment of patients with non-small cell lung cancer. However, its efficiency is limited by the development of drug resistance. Additional treatments for cases of non-small cell lung cancer relapsing with treatment with gefitinib are urgently required. To investigate the mechanisms of acquired resistance to gefitinib, we established PC-9-ZD, a human lung cancer cell line resistant to gefitinib after long-term exposure to the drug. PC-9-ZD cells showed more… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-7 of 7 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 30 references

Similar Papers

Loading similar papers…