Combined tetanus, diphtheria, and 5-component pertussis vaccine for use in adolescents and adults.

@article{Pichichero2005CombinedTD,
  title={Combined tetanus, diphtheria, and 5-component pertussis vaccine for use in adolescents and adults.},
  author={Michael E. Pichichero and Margaret B. Rennels and Kathryn Margaret Edwards and Mark M. Blatter and Gary Steven. Marshall and Monica Bologa and Elaine Ying Wang and Elaine L. Mills},
  journal={JAMA},
  year={2005},
  volume={293 24},
  pages={
          3003-11
        }
}
CONTEXT Increasing reports of pertussis among US adolescents, adults, and their infant contacts have stimulated vaccine development for older age groups. OBJECTIVE To assess the immunogenicity and reactogenicity of a tetanus-diphtheria 5-component (pertussis toxoid, filamentous hemagglutinin, pertactin, and fimbriae types 2 and 3) acellular pertussis vaccine (Tdap) in adolescents and adults. DESIGN, SETTING, AND PARTICIPANTS A prospective, randomized, modified double-blind, comparative… CONTINUE READING
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