Combined simian hemorrhagic fever and Ebola virus infection in cynomolgus monkeys.

  title={Combined simian hemorrhagic fever and Ebola virus infection in cynomolgus monkeys.},
  author={Dan W. Dalgard and Rebecca Hardy and Sonya L Pearson and G J Pucak and R V Quander and Philip M. Zack and Clarence J. Peters and Peter B Jahrling},
  journal={Laboratory animal science},
  volume={42 2},
Simian hemorrhagic fever (SHF) virus and a new strain of Ebola virus were isolated concurrently in recently imported cynomolgus monkeys (Macaca fascicularis) being maintained in a quarantine facility. Ebola virus had never been isolated in the U.S. previously and was presumed to be highly pathogenic for humans. A chronology of events including measures taken to address the public health concerns is presented. The clinicopathologic features of the disease were abrupt anorexia, splenomegaly… CONTINUE READING


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