Combined sequence-based and genetic mapping analysis of complex traits in outbred rats

Abstract

Genetic mapping on fully sequenced individuals is transforming understanding of the relationship between molecular variation and variation in complex traits. Here we report a combined sequence and genetic mapping analysis in outbred rats that maps 355 quantitative trait loci for 122 phenotypes. We identify 35 causal genes involved in 31 phenotypes… (More)
DOI: 10.1038/ng.2644

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