Combined scopolamine and morphine treatment of traumatic brain injury in the rat.

@article{Lyeth1993CombinedSA,
  title={Combined scopolamine and morphine treatment of traumatic brain injury in the rat.},
  author={Bruce G. Lyeth and Shaojun Liu and Robert J Hamm},
  journal={Brain research},
  year={1993},
  volume={617 1},
  pages={69-75}
}
Previous studies have indicated that either scopolamine (1.0 mg/kg) or morphine (10.0 mg/kg) administered to rats prior to or soon after moderate fluid percussion traumatic brain injury (TBI) reduces behavioral deficits associated with injury. In this study, a series of experiments examined the effects of a combination of these drugs, as well as each drug individually, on behavioral outcome, brain temperature, and systemic physiological responses to TBI. Experiment I: a single systemic bolus… CONTINUE READING