Combined quinacrine and chlorpromazine therapy in fatal familial insomnia.

  title={Combined quinacrine and chlorpromazine therapy in fatal familial insomnia.},
  author={Juli{\'a}n Benito-Le{\'o}n},
  journal={Clinical neuropharmacology},
  volume={27 4},
Prion diseases are invariably fatal. Recently, quinacrine and chlorpromazine have been suggested as immediate candidates for the treatment of Creutzfeldt-Jakob disease and other prion diseases. The objective of this paper was to report on 2 fatal familial insomnia patients whose overall condition worsened despite quinacrine and chlorpromazine treatment. 

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 16 extracted citations

Insights from Therapeutic Studies for PrP Prion Disease.

Cold Spring Harbor perspectives in medicine • 2017
View 2 Excerpts

Therapeutic Approaches to Prion Diseases.

Progress in molecular biology and translational science • 2017
View 1 Excerpt

Quinacrine promotes replication and conformational mutation of chronic wasting disease prions.

Proceedings of the National Academy of Sciences of the United States of America • 2014

Therapies for human prion diseases.

American journal of neurodegenerative disease • 2013
View 1 Excerpt

Similar Papers

Loading similar papers…