Combined quinacrine and chlorpromazine therapy in fatal familial insomnia.

@article{BenitoLen2004CombinedQA,
  title={Combined quinacrine and chlorpromazine therapy in fatal familial insomnia.},
  author={Juli{\'a}n Benito-Le{\'o}n},
  journal={Clinical neuropharmacology},
  year={2004},
  volume={27 4},
  pages={201-3}
}
Prion diseases are invariably fatal. Recently, quinacrine and chlorpromazine have been suggested as immediate candidates for the treatment of Creutzfeldt-Jakob disease and other prion diseases. The objective of this paper was to report on 2 fatal familial insomnia patients whose overall condition worsened despite quinacrine and chlorpromazine treatment. 

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Insights from Therapeutic Studies for PrP Prion Disease.

Cold Spring Harbor perspectives in medicine • 2017
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Quinacrine promotes replication and conformational mutation of chronic wasting disease prions.

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Therapies for human prion diseases.

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